BDBM327892 4-((2-(5-(4-(4- fluorobenzyl)piperazine- 1-carbonyl)pyridin-2-yl)- 2,8- diazaspiro[4.5]decan-8- yl)methyl)benzonitrile::US9663496, Compound 31

SMILES Fc1ccc(CN2CCN(CC2)C(=O)c2ccc(nc2)N2CCC3(C2)CCN(Cc2ccc(cc2)C#N)CC3)cc1

InChI Key InChIKey=OLOFHQKCBQKIAJ-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 327892   

Target5'-AMP-activated protein kinase catalytic subunit alpha-2(Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM327892(4-((2-(5-(4-(4- fluorobenzyl)piperazine- 1-carbony...)
Affinity DataEC50: <500nMAssay Description:Compounds were assayed for their ability to activate AMPK using an enzyme-linked immunosorbent assay. Reagents and procedures for measuring AMPK acti...More data for this Ligand-Target Pair
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Date in BDB:
6/4/2019
Entry Details
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