BDBM327873 5-(4-(4- fluorobenzyl)piperazine- 1-carbonyl-N-(3- phenylphenyl) picolinamide::US10377742, Compound 12::US9663496, Compound 12

SMILES Fc1ccc(CN2CCN(CC2)C(=O)c2ccc(nc2)C(=O)Nc2cccc(c2)-c2ccccc2)cc1

InChI Key InChIKey=DEAYGZRRXFNGTA-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 327873   

Target5'-AMP-activated protein kinase catalytic subunit alpha-2(Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM327873(5-(4-(4- fluorobenzyl)piperazine- 1-carbonyl-N-(3-...)
Affinity DataEC50:  7.50E+3nMAssay Description:Compounds were assayed for their ability to activate AMPK using an enzyme-linked immunosorbent assay. Reagents and procedures for measuring AMPK acti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
Go to US Patent

Target5'-AMP-activated protein kinase catalytic subunit alpha-2(Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM327873(5-(4-(4- fluorobenzyl)piperazine- 1-carbonyl-N-(3-...)
Affinity DataEC50:  7.50E+3nMAssay Description:Compounds were assayed for their ability to activate AMPK using an enzyme-linked immunosorbent assay. Reagents and procedures for measuring AMPK acti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
Go to US Patent