BDBM327865 N-(1-(4- cyanobenzoyl)piperidin- 4-yl)-5-(4-(4- fluorobenzyl)piperazine- 1-carbonyl)picolinamide::US10377742, Compound 4::US9663496, Compound 4

SMILES Fc1ccc(CN2CCN(CC2)C(=O)c2ccc(nc2)C(=O)NC2CCN(CC2)C(=O)c2ccc(cc2)C#N)cc1

InChI Key InChIKey=AIJFSOPJUPPZAC-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 327865   

Target5'-AMP-activated protein kinase catalytic subunit alpha-2(Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM327865(N-(1-(4- cyanobenzoyl)piperidin- 4-yl)-5-(4-(4- fl...)
Affinity DataEC50:  750nMAssay Description:Compounds were assayed for their ability to activate AMPK using an enzyme-linked immunosorbent assay. Reagents and procedures for measuring AMPK acti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
Go to US Patent

Target5'-AMP-activated protein kinase catalytic subunit alpha-2(Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM327865(N-(1-(4- cyanobenzoyl)piperidin- 4-yl)-5-(4-(4- fl...)
Affinity DataEC50:  750nMAssay Description:Compounds were assayed for their ability to activate AMPK using an enzyme-linked immunosorbent assay. Reagents and procedures for measuring AMPK acti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
Go to US Patent