BDBM327844 2-((R)-4-(cyclopropyl(3-(trifluoromethyl)phenyl)methyl)-2-methylpiperazin-1-yl)acetic acid::US9663476, Compound 77

SMILES C[C@@H]1CN(CCN1CC(O)=O)C(C1CC1)c1cccc(c1)C(F)(F)F

InChI Key InChIKey=BHYTUTVYZHKTTJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 327844   

LigandPNGBDBM327844(2-((R)-4-(cyclopropyl(3-(trifluoromethyl)phenyl)me...)
Affinity DataIC50: 1.5nMAssay Description:This cell-based assay measures the ability of test compounds to inhibit the uptake of glycine by the glycine transporter type 1. Human placental chor...More data for this Ligand-Target Pair
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Date in BDB:
6/4/2019
Entry Details
Go to US Patent