BDBM327839 US9663476, Compound 48::[(R)-2-methyl-4-[(R)-(3′-methyl-biphenyl-4-yl)-phenyl-methyl]-piperazin-1-yl]-acetic acid

SMILES C[C@@H]1CN(CCN1CC(O)=O)[C@H](c1ccccc1)c1ccc(cc1)-c1cccc(C)c1

InChI Key InChIKey=UJFSHJIHSJJHAL-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 327839   

TargetSodium- and chloride-dependent glycine transporter 1(Human)
Amgen

US Patent

LigandBDBM327839([(R)-2-methyl-4-[(R)-(3′-methyl-biphenyl-4-y...)Copy SMILESCopy InChI

Affinity DataIC50: 217nMAssay Description:This cell-based assay measures the ability of test compounds to inhibit the uptake of glycine by the glycine transporter type 1. Human placental chor...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
6/4/2019
Entry Details
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