BDBM327789 US9663475, Compound A8::US9663475, Compound A9

SMILES COc1cc2CC(Cc2cc1OC)N1Cc2ccc(Cl)cc2N=C1N

InChI Key InChIKey=NYXMXXMYBZMBHH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 327789   

TargetCathepsin D(Human)
Merck Patent

US Patent
LigandPNGBDBM327789(US9663475, Compound A9 | US9663475, Compound A8)
Affinity DataIC50: 1.10E+3nMAssay Description:In order to identify modulators of cathepsin D activity, a continuous enzymatic test was carried out with a synthetic peptide which carries a fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
Go to US Patent

TargetCathepsin D(Human)
Merck Patent

US Patent
LigandPNGBDBM327789(US9663475, Compound A9 | US9663475, Compound A8)
Affinity DataIC50: 510nMAssay Description:In order to identify modulators of cathepsin D activity, a continuous enzymatic test was carried out with a synthetic peptide which carries a fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
Go to US Patent