BDBM327467 2-chloro-4-[[2-[1-(cyclohexylmethyl)-4-piperidyl]ethyl]-N-methoxycarbonimidoyl]-5-methoxyaniline::US9663465, 24

SMILES CON=C(CCC1CCN(CC2CCCCC2)CC1)c1cc(Cl)c(N)cc1OC

InChI Key InChIKey=ZAKCOJKXWMIQSX-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 327467   

TargetAcetylcholinesterase(Human)
Universite De Caen

US Patent
LigandPNGBDBM327467( 2-chloro-4-[[2-[1-(cyclohexylmethyl)-4-piperidyl]...)
Affinity DataIC50: 320nMAssay Description:Acetylcholinesterase extracted from human erythrocytes (buffered aqueous solution, ≧500 units/mg, Sigma Aldrich) is diluted in a 20 mM HEPES bu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2019
Entry Details
Go to US Patent

Target5-hydroxytryptamine receptor 4(Human)
Universite De Caen

US Patent
LigandPNGBDBM327467( 2-chloro-4-[[2-[1-(cyclohexylmethyl)-4-piperidyl]...)
Affinity DataKi:  13.1nMAssay Description:Prior to these competition studies, a series of saturation curves were performed in order to check whether the pharmacological parameters Kd, Bmax an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2019
Entry Details
Go to US Patent