BDBM327461 4-amino-5-bromo-N-[[1-(cyclohexylmethyl)-4-piperidyl]methyl]-2-methoxybenzamide::US9663465, 18

SMILES COc1cc(N)c(Br)cc1C(=O)NCC1CCN(CC2CCCCC2)CC1

InChI Key InChIKey=MOOXZLVIEUWOJV-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 327461   

TargetAcetylcholinesterase(Human)
Universite De Caen

US Patent
LigandPNGBDBM327461(4-amino-5-bromo-N-[[1-(cyclohexylmethyl)-4-piperid...)
Affinity DataIC50: 8.70E+3nMAssay Description:Acetylcholinesterase extracted from human erythrocytes (buffered aqueous solution, ≧500 units/mg, Sigma Aldrich) is diluted in a 20 mM HEPES bu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2019
Entry Details
Go to US Patent

Target5-hydroxytryptamine receptor 4(Human)
Universite De Caen

US Patent
LigandPNGBDBM327461(4-amino-5-bromo-N-[[1-(cyclohexylmethyl)-4-piperid...)
Affinity DataKi:  5.40nMAssay Description:Prior to these competition studies, a series of saturation curves were performed in order to check whether the pharmacological parameters Kd, Bmax an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2019
Entry Details
Go to US Patent