BDBM327453 1-(4-amino-5-chloro-2-methoxyphenyl)-3-[1-(cyclohexylmethyl)-4-piperidyl]-2 methylpropan-1-one::US9663465, 10

SMILES COc1cc(N)c(Cl)cc1C(=O)C(C)CC1CCN(CC2CCCCC2)CC1

InChI Key InChIKey=PCGROECTIBEWPF-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 327453   

TargetAcetylcholinesterase(Human)
Universite De Caen

US Patent
LigandPNGBDBM327453(1-(4-amino-5-chloro-2-methoxyphenyl)-3-[1-(cyclohe...)
Affinity DataIC50: 201nMAssay Description:Acetylcholinesterase extracted from human erythrocytes (buffered aqueous solution, ≧500 units/mg, Sigma Aldrich) is diluted in a 20 mM HEPES bu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2019
Entry Details
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Target5-hydroxytryptamine receptor 4(Human)
Universite De Caen

US Patent
LigandPNGBDBM327453(1-(4-amino-5-chloro-2-methoxyphenyl)-3-[1-(cyclohe...)
Affinity DataKi:  125nMAssay Description:Prior to these competition studies, a series of saturation curves were performed in order to check whether the pharmacological parameters Kd, Bmax an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2019
Entry Details
Go to US Patent