BDBM327446 1-(4-amino-5-iodo-2-methoxyphenyl)-3-[1-butyl-4-piperidyl]propan-1-one::US9663465, 3

SMILES CCCCN1CCC(CCC(=O)c2cc(I)c(N)cc2OC)CC1

InChI Key InChIKey=AEHUGLUJLXQXMZ-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 327446   

TargetAcetylcholinesterase(Human)
Universite De Caen

US Patent
LigandPNGBDBM327446(1-(4-amino-5-iodo-2-methoxyphenyl)-3-[1-butyl-4-pi...)
Affinity DataIC50: 658nMAssay Description:Acetylcholinesterase extracted from human erythrocytes (buffered aqueous solution, ≧500 units/mg, Sigma Aldrich) is diluted in a 20 mM HEPES bu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2019
Entry Details
Go to US Patent

Target5-hydroxytryptamine receptor 4(Human)
Universite De Caen

US Patent
LigandPNGBDBM327446(1-(4-amino-5-iodo-2-methoxyphenyl)-3-[1-butyl-4-pi...)
Affinity DataKi:  44.7nMAssay Description:Prior to these competition studies, a series of saturation curves were performed in order to check whether the pharmacological parameters Kd, Bmax an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2019
Entry Details
Go to US Patent