BDBM32740 MLS000556530::N-[2-Methoxy-5-(3-methyl-4-oxo-3,4-dihydro-phthalazin-1-yl)-phenyl]-2-(4-methoxy-phenoxy)-acetamide::N-[2-methoxy-5-(3-methyl-4-oxidanylidene-phthalazin-1-yl)phenyl]-2-(4-methoxyphenoxy)ethanamide::N-[2-methoxy-5-(3-methyl-4-oxo-1-phthalazinyl)phenyl]-2-(4-methoxyphenoxy)acetamide::N-[2-methoxy-5-(3-methyl-4-oxophthalazin-1-yl)phenyl]-2-(4-methoxyphenoxy)acetamide::N-[5-(4-keto-3-methyl-phthalazin-1-yl)-2-methoxy-phenyl]-2-(4-methoxyphenoxy)acetamide::SMR000147847::cid_1862698

SMILES COc1ccc(OCC(=O)Nc2cc(ccc2OC)-c2nn(C)c(=O)c3ccccc23)cc1

InChI Key InChIKey=FTWWXBRJAWFLBD-UHFFFAOYSA-N

Data  2 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 32740   

TargetCoagulation factor XI(Human)
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM32740(N-[2-Methoxy-5-(3-methyl-4-oxo-3,4-dihydro-phthala...)
Affinity DataIC50: 5.00E+4nMpH: 7.4 T: 2°CAssay Description:Factor XIa (0.23 ug/mL) was incubated with Boc-Glu-Ala-Arg-AMC substrate (15 uM) in 10 uL of assay buffer for 2 hr at room temperature. Read fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2009
Entry Details
PCBioAssay
TargetCoagulation factor XI(Human)
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM32740(N-[2-Methoxy-5-(3-methyl-4-oxo-3,4-dihydro-phthala...)
Affinity DataIC50: 5.00E+4nMAssay Description:Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Scott L. Diamond, University of Pennsy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2011
Entry Details
PCBioAssay
TargetNuclear receptor coactivator 1(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM32740(N-[2-Methoxy-5-(3-methyl-4-oxo-3,4-dihydro-phthala...)
Affinity DataEC50:  6.26E+4nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute (TSRI) Assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2011
Entry Details
PCBioAssay
TargetNuclear receptor coactivator 3(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM32740(N-[2-Methoxy-5-(3-methyl-4-oxo-3,4-dihydro-phthala...)
Affinity DataEC50:  7.66E+4nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center http://molscreen.florida.scripps.edu/ Center Affiliation: The ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2011
Entry Details
PCBioAssay
TargetNuclear receptor coactivator 2(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM32740(N-[2-Methoxy-5-(3-methyl-4-oxo-3,4-dihydro-phthala...)
Affinity DataEC50:  3.12E+4nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute (TSRI) Assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2011
Entry Details
PCBioAssay