BDBM32738 6,8-Diamino-4-(2-chloro-phenyl)-9-imino-2-oxo-1,3,4,9-tetrahydro-2H-10-thia-1,5-diaza-phenanthrene- 7-carbonitrile::MLS000556518::SMR000147835::cid_9551738

SMILES NC1=c2c(N)c(C#N)c(N)nc2=C2C(CC(=O)N=C2S1)c1ccccc1Cl

InChI Key InChIKey=DDGBHJLJLPZPIM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 32738   

TargetCoagulation factor XI(Human)
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM32738(SMR000147835 | 6,8-Diamino-4-(2-chloro-phenyl)-9-i...)
Affinity DataIC50: 5.00E+4nMpH: 7.4 T: 2°CAssay Description:Factor XIa (0.23 ug/mL) was incubated with Boc-Glu-Ala-Arg-AMC substrate (15 uM) in 10 uL of assay buffer for 2 hr at room temperature. Read fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2009
Entry Details
PCBioAssay
TargetCoagulation factor XI(Human)
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM32738(SMR000147835 | 6,8-Diamino-4-(2-chloro-phenyl)-9-i...)
Affinity DataIC50: 5.00E+4nMAssay Description:Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Scott L. Diamond, University of Pennsy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2011
Entry Details
PCBioAssay