BDBM327137 4-(1-{4-[(3S)-2,3- dihydro[1,4]dioxino[2,3- b]pyridin-3-yl]benzyl}piperidin-4- yl)benzoic acid::US11957671, Compound 235::US9662339, 235

SMILES OC(=O)c1ccc(cc1)C1CCN(Cc2ccc(cc2)[C@H]2COc3cccnc3O2)CC1

InChI Key InChIKey=QBKMHUZIIFEQEP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 327137   

TargetLeukotriene A-4 hydrolase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM327137(4-(1-{4-[(3S)-2,3- dihydro[1,4]dioxino[2,3- b]py...)
Affinity DataIC50: 0.0800nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2019
Entry Details
Go to US Patent

TargetLeukotriene A-4 hydrolase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM327137(4-(1-{4-[(3S)-2,3- dihydro[1,4]dioxino[2,3- b]py...)
Affinity DataIC50: 0.0800nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
Go to US Patent