BDBM32674 1-benzotriazolyl-(1-phenyl-3-pyridin-4-yl-4-pyrazolyl)methanone::1-{[1-phenyl-3-(4-pyridinyl)-1H-pyrazol-4-yl]carbonyl}-1H-1,2,3-benzotriazole::MLS000049336::SMR000075218::benzotriazol-1-yl-(1-phenyl-3-pyridin-4-yl-pyrazol-4-yl)methanone::benzotriazol-1-yl-(1-phenyl-3-pyridin-4-ylpyrazol-4-yl)methanone::benzotriazol-1-yl-[1-phenyl-3-(4-pyridyl)pyrazol-4-yl]methanone::cid_1307930

SMILES O=C(c1cn(nc1-c1ccncc1)-c1ccccc1)n1nnc2ccccc12

InChI Key InChIKey=XKJPYUYSROHYIL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 32674   

TargetCoagulation factor XII(Human)
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM32674(1-{[1-phenyl-3-(4-pyridinyl)-1H-pyrazol-4-yl]carbo...)
Affinity DataIC50: 973nMpH: 7.4 T: 2°CAssay Description:HTS was performed on a total of 33,068 compounds of the MLSCN library, 23,017 of which were not in the mixture HTS plates used previously. These comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2009
Entry Details
PCBioAssay
TargetCoagulation factor XI(Human)
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM32674(1-{[1-phenyl-3-(4-pyridinyl)-1H-pyrazol-4-yl]carbo...)
Affinity DataIC50: 707nMpH: 7.4 T: 2°CAssay Description:Factor XIa (0.23 ug/mL) was incubated with Boc-Glu-Ala-Arg-AMC substrate (15 uM) in 10 uL of assay buffer for 2 hr at room temperature. Read fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2009
Entry Details
PCBioAssay
TargetCoagulation factor XI(Human)
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM32674(1-{[1-phenyl-3-(4-pyridinyl)-1H-pyrazol-4-yl]carbo...)
Affinity DataIC50: 707nMAssay Description:Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Scott L. Diamond, University of Pennsy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2011
Entry Details
PCBioAssay