BDBM326214 (R)-(3-(7-amino-1-(4-(4-fluorophenoxy)phenyl)-1H-pyrazolo[3,4-c]pyridin-3-yl)piperidin-1-yl)(3-methyloxetan-3-yl)methanone::US9637486, Example 26

SMILES CC1(COC1)C(=O)N1CCC[C@H](C1)c1nn(-c2ccc(Oc3ccc(F)cc3)cc2)c2c(N)nccc12

InChI Key InChIKey=YHCQFHRYTXITTH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 326214   

TargetTyrosine-protein kinase BTK(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM326214((R)-(3-(7-amino-1-(4-(4-fluorophenoxy)phenyl)-1H-p...)
Affinity DataIC50: 56.9nMAssay Description:In this assay, the potency (IC50) of each compound was determined from an eleven point (1:3 serial dilution; final compound concentration range in as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
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