BDBM326213 1-(4-phenoxyphenyl)-3- [(3R)-piperidin-3-yl]-1H- pyrazolo[3,4-c]pyridin-7- amine::US9637486, Example 25

SMILES Nc1nccc2c(nn(-c3ccc(Oc4ccccc4)cc3)c12)[C@@H]1CCCNC1

InChI Key InChIKey=LFLVNDPKEGNVHV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 326213   

TargetTyrosine-protein kinase BTK(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM326213(1-(4-phenoxyphenyl)-3- [(3R)-piperidin-3-yl]-1H- p...)
Affinity DataIC50: 30.8nMAssay Description:In this assay, the potency (IC50) of each compound was determined from an eleven point (1:3 serial dilution; final compound concentration range in as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
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