BDBM3261 4-Anilino quinazoline deriv. 12::N-(3-methoxyphenyl)quinazolin-4-amine

SMILES COc1cccc(Nc2ncnc3ccccc23)c1

InChI Key InChIKey=LCYPRFCDTJTQPG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 3261   

TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM3261(N-(3-methoxyphenyl)quinazolin-4-amine | 4-Anilino ...)
Affinity DataIC50: 842nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2005
Entry Details Article
PubMed
LigandPNGBDBM3261(N-(3-methoxyphenyl)quinazolin-4-amine | 4-Anilino ...)
Affinity DataIC50: 645nMAssay Description:Inhibition of GFP-fused human ABCG2 expressed in MDCK2 cells assessed as Hoechst 33342 accumulation preincubated for 30 mins followed by Hoechst 3334...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed