BDBM326039 1-({(3R)-3-[7-amino-1-(4- phenoxyphenyl)-1H- pyrazolo[3,4-c]pyridin-3- yl]piperidin-1- yl}carbonyl)cyclopropane carbonitrile::US9637486, Example 10

SMILES Nc1nccc2c(nn(-c3ccc(Oc4ccccc4)cc3)c12)[C@@H]1CCCN(C1)C(=O)C1(CC1)C#N

InChI Key InChIKey=LAELGOCGBXCISU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 326039   

TargetTyrosine-protein kinase BTK(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM326039(1-({(3R)-3-[7-amino-1-(4- phenoxyphenyl)-1H- pyraz...)
Affinity DataIC50: 11.8nMAssay Description:In this assay, the potency (IC50) of each compound was determined from an eleven point (1:3 serial dilution; final compound concentration range in as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
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