BDBM325768 (rac)-1-(Azetidin-1-yl)-2-[4-[2-fluoro-4-(trifluoromethyl)phenyl]-6,7-dihydro-5H-cyclopenta[c]pyridin-7-yl]ethanone::US9636339, 18

SMILES Fc1cc(ccc1-c1cncc2C(CC(=O)N3CCC3)CCc12)C(F)(F)F

InChI Key InChIKey=JNXJOKUYAAGRDD-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 325768   

TargetCytochrome P450 11B1, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM325768((rac)-1-(Azetidin-1-yl)-2-[4-[2-fluoro-4-(trifluor...)
Affinity DataEC50:  2.68E+3nMAssay Description:G-402 cells expressing CYP11 constructs were established as described above and maintained in McCoy's 5a Medium Modified, ATCC Catalog No. 30-200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
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TargetCytochrome P450 11B2, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM325768((rac)-1-(Azetidin-1-yl)-2-[4-[2-fluoro-4-(trifluor...)
Affinity DataEC50:  48nMAssay Description:G-402 cells expressing CYP11 constructs were established as described above and maintained in McCoy's 5a Medium Modified, ATCC Catalog No. 30-200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
Go to US Patent