BDBM324250 US10189819, Example 104

SMILES OC(=O)c1ccc2ncn(-c3ccc(C(=O)NCC(c4cccc(F)c4)c4nc5c(F)ccc(Cl)c5c(=O)[nH]4)c(Cl)c3)c2c1

InChI Key InChIKey=NXXPGGMVLWDNKK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 324250   

TargetCoagulation factor IX(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM324250(US10189819, Example 104)
Affinity DataIC50: 1.97nMAssay Description:Formation of a clot to stem bleeding at a site of blood vessel injury involves the coordinated activity of a group of plasma proteins that initiate a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
Go to US Patent