BDBM32393 carboxamide, 12b

SMILES O=C(Cc1ccccc1)N(CCCNCCN(Cc1ccccc1)C(=O)Cc1ccccc1)Cc1ccccc1

InChI Key InChIKey=YNSUWYUSGRDYGA-UHFFFAOYSA-N

Data  2 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 32393   

TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Philipps University Marburg

LigandPNGBDBM32393(carboxamide, 12b)
Affinity DataIC50: 2.50E+5nMpH: 5.5 T: 2°CAssay Description:Enzyme assay was performed at room temperature on a microplate reader (Safire2TM) using black 96-well microtiter plates purchased from Nunc. Inhibito...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2009
Entry Details Article
PubMed
TargetRenin(Human)
Philipps University Marburg

LigandPNGBDBM32393(carboxamide, 12b)
Affinity DataIC50: 2.50E+5nMT: 2°CAssay Description:Enzyme assay was performed at room temperature on a microplate reader (Safire2TM) using black 96-well microtiter plates purchased from Nunc. Inhibito...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2009
Entry Details Article
PubMed
TargetBeta-secretase 1 [22-457](Human)
Philipps University Marburg

LigandPNGBDBM32393(carboxamide, 12b)
Affinity DataIC50: 2.50E+5nMT: 2°CAssay Description:Enzyme assay was performed at room temperature on a microplate reader (Safire2TM) using black 96-well microtiter plates purchased from Nunc. Inhibito...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2009
Entry Details Article
PubMed
TargetPepsin A(Pig)
Philipps University Marburg

LigandPNGBDBM32393(carboxamide, 12b)
Affinity DataIC50: 2.50E+5nMT: 2°CAssay Description:Enzyme assay was performed at room temperature on a microplate reader (Safire2TM) using black 96-well microtiter plates purchased from Nunc. Inhibito...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2009
Entry Details Article
PubMed
TargetPlasmepsin IV(Plasmodium falciparum (isolate 3D7))
Philipps University Marburg

LigandPNGBDBM32393(carboxamide, 12b)
Affinity DataKi:  5.60E+4nM ΔG°:  -5.80kcal/moleT: 2°CAssay Description:Enzyme assay was performed at room temperature on a microplate reader (Safire2TM) using black 96-well microtiter plates purchased from Nunc. Inhibito...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2009
Entry Details Article
PubMed
TargetPlasmepsin II(Plasmodium falciparum)
Philipps University Marburg

LigandPNGBDBM32393(carboxamide, 12b)
Affinity DataKi:  6.30E+4nM ΔG°:  -5.69kcal/molepH: 4.5 T: 2°CAssay Description:Enzyme assay was performed at room temperature on a microplate reader (Safire2TM) using black 96-well microtiter plates purchased from Nunc. Inhibito...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2009
Entry Details Article
PubMed