BDBM323770 Sodium 4-{[(6-bromo-3-methyl-2-phenylquinolin-4-yl)carbonyl]amino}-3-fluorobenzoate::US10189788, Example 50::US10189788, Example 69::US10189788, Example 71

SMILES Cc1c(nc2ccc(Br)cc2c1C(=O)Nc1ccc(cc1F)C([O-])=O)-c1ccccc1

InChI Key InChIKey=LCFQGSRRJKESSW-UHFFFAOYSA-M

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 323770   

TargetProstaglandin F2-alpha receptor(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM323770(US10189788, Example 50 | US10189788, Example 71 | ...)
Affinity DataIC50: 37nMAssay Description:For the characterization of test substances in respect of FP antagonism, PGF2α-induced calcium flux in FP-expressing CHEM1 cells (Millipore, HTS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
Go to US Patent

TargetProstaglandin F2-alpha receptor(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM323770(US10189788, Example 50 | US10189788, Example 71 | ...)
Affinity DataIC50: 104nMAssay Description:For the characterization of test substances in respect of FP antagonism, PGF2α-induced calcium flux in FP-expressing CHEM1 cells (Millipore, HTS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
Go to US Patent

TargetProstaglandin F2-alpha receptor(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM323770(US10189788, Example 50 | US10189788, Example 71 | ...)
Affinity DataIC50: 90nMAssay Description:For the characterization of test substances in respect of FP antagonism, PGF2α-induced calcium flux in FP-expressing CHEM1 cells (Millipore, HTS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
Go to US Patent

TargetProstaglandin F2-alpha receptor(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM323770(US10189788, Example 50 | US10189788, Example 71 | ...)
Affinity DataIC50: 44nMAssay Description:For the characterization of test substances in respect of FP antagonism, the PGF2α-induced calcium flux in recombinant FP-expressing CHO cells w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
Go to US Patent

TargetProstaglandin F2-alpha receptor(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM323770(US10189788, Example 50 | US10189788, Example 71 | ...)
Affinity DataIC50: 59nMAssay Description:For the characterization of test substances in respect of FP antagonism, the PGF2α-induced calcium flux in recombinant FP-expressing CHO cells w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
Go to US Patent

TargetProstaglandin F2-alpha receptor(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM323770(US10189788, Example 50 | US10189788, Example 71 | ...)
Affinity DataIC50: 47nMAssay Description:For the characterization of test substances in respect of FP antagonism, the PGF2α-induced calcium flux in recombinant FP-expressing CHO cells w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
Go to US Patent