BDBM323659 (R)-2-(3-(2- ethoxyphenoxy)piperidin- 1-yl)-N-(3-(methylamino)- 3-oxopropyl)pyrimidine- 5-carboxamide::US10188653, Example 20.4::US9789110, 20.4

SMILES CCOc1ccccc1O[C@@H]1CCCN(C1)c1ncc(cn1)C(=O)NCCC(=O)NC

InChI Key InChIKey=PGILSSPBYSJVBW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 323659   

TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandPNGBDBM323659((R)-2-(3-(2- ethoxyphenoxy)piperidin- 1-yl)-N-(3-(...)
Affinity DataIC50: 53.3nMAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
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TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandPNGBDBM323659((R)-2-(3-(2- ethoxyphenoxy)piperidin- 1-yl)-N-(3-(...)
Affinity DataIC50: 53.3nMAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
Go to US Patent