BDBM323498 2-(3-(Benzyloxy)Phenoxy)Ethanamine::US10188615, Example 8::US10639286, Example 8

SMILES NCCOc1cccc(OCc2ccccc2)c1

InChI Key InChIKey=LIOIJJQQKDMYBJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 323498   

TargetRetinoid isomerohydrolase(Human)
Acucela

US Patent
LigandPNGBDBM323498(2-(3-(Benzyloxy)Phenoxy)Ethanamine | US10188615, E...)
Affinity DataIC50: 550nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
Go to US Patent

TargetRetinoid isomerohydrolase(Bovine)
Acucela

US Patent
LigandPNGBDBM323498(2-(3-(Benzyloxy)Phenoxy)Ethanamine | US10188615, E...)
Affinity DataIC50: 5.50E+3nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
Go to US Patent

TargetRetinaldehyde-binding protein 1(Bovine)
Acucela

US Patent
LigandPNGBDBM323498(2-(3-(Benzyloxy)Phenoxy)Ethanamine | US10188615, E...)
Affinity DataIC50: 5.50E+3nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J Biol. Chem. 274:8577-85 (1999).More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2021
Entry Details
Go to US Patent

TargetRetinaldehyde-binding protein 1(Human)
Acucela

US Patent
LigandPNGBDBM323498(2-(3-(Benzyloxy)Phenoxy)Ethanamine | US10188615, E...)
Affinity DataIC50: 550nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J Biol. Chem. 274:8577-85 (1999).More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2021
Entry Details
Go to US Patent