BDBM32322 2-[(3-pyridin-2-yl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)sulfanyl]-N-(1,3-thiazol-2-yl)acetamide::2-[(3-pyridin-2-yl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)sulfanyl]-N-(1,3-thiazol-2-yl)ethanamide::2-[[3-(2-pyridinyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl]thio]-N-(2-thiazolyl)acetamide::2-[[3-(2-pyridyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl]thio]-N-thiazol-2-yl-acetamide::MLS000419537::SMR000320325::cid_7190519

SMILES O=C(CSc1ccc2nnc(-c3ccccn3)n2n1)Nc1nccs1

InChI Key InChIKey=PFKVOHSTBPESRQ-UHFFFAOYSA-N

Data  5 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 32322   

LigandPNGBDBM32322(2-[[3-(2-pyridinyl)-[1,2,4]triazolo[4,3-b]pyridazi...)
Affinity DataEC50:  1.13E+4nMpH: 7.4 T: 2°CAssay Description:The HTS assay was conducted in 384-well microplates in a total assay volume per well of 10.1 microliters (5 microliters of bead mixture, 0.1 microlit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2009
Entry Details
PCBioAssay
LigandPNGBDBM32322(2-[[3-(2-pyridinyl)-[1,2,4]triazolo[4,3-b]pyridazi...)
Affinity DataEC50:  5.54E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2011
Entry Details
PCBioAssay
TargetBcl-2-like protein 2(Human)
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM32322(2-[[3-(2-pyridinyl)-[1,2,4]triazolo[4,3-b]pyridazi...)
Affinity DataEC50:  1.41E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2011
Entry Details
PCBioAssay
LigandPNGBDBM32322(2-[[3-(2-pyridinyl)-[1,2,4]triazolo[4,3-b]pyridazi...)
Affinity DataEC50:  1.18E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2011
Entry Details
PCBioAssay
LigandPNGBDBM32322(2-[[3-(2-pyridinyl)-[1,2,4]triazolo[4,3-b]pyridazi...)
Affinity DataEC50:  1.30E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2011
Entry Details
PCBioAssay