BDBM32316 MLS000704595::SMR000231990::cid_5774988::ethyl 6-chloro-2,7-dioxo-2,7-dihydro-3H-naphtho[1,2,3-de]quinoline-1-carboxylate

SMILES CCOC(=O)c1c2-c3ccccc3C(=O)c3c(Cl)ccc([nH]c1=O)c23

InChI Key InChIKey=CELQOEJPNANKNS-UHFFFAOYSA-N

Data  2 IC50  7 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 32316   

LigandPNGBDBM32316(MLS000704595 | SMR000231990 | ethyl 6-chloro-2,7-d...)
Affinity DataEC50:  5.86E+3nMpH: 7.4 T: 2°CAssay Description:The HTS assay was conducted in 384-well microplates in a total assay volume per well of 10.1 microliters (5 microliters of bead mixture, 0.1 microlit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2009
Entry Details
PCBioAssay
LigandPNGBDBM32316(MLS000704595 | SMR000231990 | ethyl 6-chloro-2,7-d...)
Affinity DataEC50:  5.40E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2011
Entry Details
PCBioAssay
LigandPNGBDBM32316(MLS000704595 | SMR000231990 | ethyl 6-chloro-2,7-d...)
Affinity DataEC50:  1.32E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2011
Entry Details
PCBioAssay
TargetBcl-2-like protein 2(Human)
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM32316(MLS000704595 | SMR000231990 | ethyl 6-chloro-2,7-d...)
Affinity DataEC50:  6.14E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2011
Entry Details
PCBioAssay
TargetApoptosis regulator Bcl-2(Human)
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM32316(MLS000704595 | SMR000231990 | ethyl 6-chloro-2,7-d...)
Affinity DataEC50:  7.65E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2011
Entry Details
PCBioAssay
LigandPNGBDBM32316(MLS000704595 | SMR000231990 | ethyl 6-chloro-2,7-d...)
Affinity DataEC50:  9.29E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2011
Entry Details
PCBioAssay
LigandPNGBDBM32316(MLS000704595 | SMR000231990 | ethyl 6-chloro-2,7-d...)
Affinity DataEC50:  400nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2011
Entry Details
PCBioAssay
TargetSentrin-specific protease 1(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM32316(MLS000704595 | SMR000231990 | ethyl 6-chloro-2,7-d...)
Affinity DataIC50: 2.75E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2013
Entry Details
PCBioAssay
TargetSentrin-specific protease 1(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM32316(MLS000704595 | SMR000231990 | ethyl 6-chloro-2,7-d...)
Affinity DataIC50: 1.83E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2013
Entry Details
PCBioAssay