BDBM32315 CHEMBL1345690::MLS000715851::SMR000277368::cid_5522952

SMILES CCOC(=O)c1c2-c3ccccc3C(=O)c3cccc([nH]c1=O)c23

InChI Key InChIKey=UFJGFNHRMPMALC-UHFFFAOYSA-N

Data  1 KI  1 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 32315   

LigandPNGBDBM32315(CHEMBL1345690 | MLS000715851 | SMR000277368 | cid_...)
Affinity DataEC50:  2.12E+3nMpH: 7.4 T: 2°CAssay Description:The HTS assay was conducted in 384-well microplates in a total assay volume per well of 10.1 microliters (5 microliters of bead mixture, 0.1 microlit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2009
Entry Details
PCBioAssay
LigandPNGBDBM32315(CHEMBL1345690 | MLS000715851 | SMR000277368 | cid_...)
Affinity DataEC50:  5.11E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2011
Entry Details
PCBioAssay
LigandPNGBDBM32315(CHEMBL1345690 | MLS000715851 | SMR000277368 | cid_...)
Affinity DataEC50:  3.53E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2011
Entry Details
PCBioAssay
TargetMitogen-activated protein kinase kinase kinase 5(Human)
Nas of Ukraine

Curated by ChEMBL
LigandPNGBDBM32315(CHEMBL1345690 | MLS000715851 | SMR000277368 | cid_...)
Affinity DataIC50: 3.00E+3nMAssay Description:Competitive inhibition of human ASK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
Nas of Ukraine

Curated by ChEMBL
LigandPNGBDBM32315(CHEMBL1345690 | MLS000715851 | SMR000277368 | cid_...)
Affinity DataKi:  500nMAssay Description:Competitive inhibition of human ASK1 by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed