BDBM323113 4-((trans-4-(3,4-dichlorophenyl)piperidin-3-yl)methoxy)-2,5-difluoro-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide::US9630929, Example 92

SMILES Fc1cc(c(F)cc1OC[C@@H]1CNCCC1c1ccc(Cl)c(Cl)c1)S(=O)(=O)Nc1ncns1

InChI Key InChIKey=JVNFXYUGRQQZML-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 323113   

TargetSodium channel protein type 9 subunit alpha(Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM323113(4-((trans-4-(3,4-dichlorophenyl)piperidin-3-yl)met...)
Affinity DataIC50: 100nMAssay Description:The following patch voltage clamp electrophysiology studies were performed on representative compounds of the invention using human embryonic kidney ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2019
Entry Details
Go to US Patent

TargetSodium channel protein type 9 subunit alpha(Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM323113(4-((trans-4-(3,4-dichlorophenyl)piperidin-3-yl)met...)
Affinity DataIC50: 0.800nMAssay Description:The following patch voltage clamp electrophysiology studies were performed on representative compounds of the invention using human embryonic kidney ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2019
Entry Details
Go to US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM323113(4-((trans-4-(3,4-dichlorophenyl)piperidin-3-yl)met...)
Affinity DataIC50: 1.00E+4nMAssay Description:The following patch voltage clamp electrophysiology studies were performed on representative compounds of the invention using human embryonic kidney ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2019
Entry Details
Go to US Patent