BDBM322747 2-(1-(4-((2-(3,5-dimethylpiperidin-1-yl)- 5-oxo-5,6-dihydropyrimido[4,5- d]pyridazin-4-yl)amino)phenyl)piperidin- 4-yl)acetic acid::US10183944, Example 117::US10647720, Ex. # 117
SMILES CC1CC(C)CN(C1)c1nc(Nc2ccc(cc2)N2CCC(CC(O)=O)CC2)c2c(cn[nH]c2=O)n1
InChI Key InChIKey=YBTVYOBZIFTKHY-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 322747
Affinity DataIC50: 50nMAssay Description:2.5 μL of 10% DMSO or compound in 10% DMSO was added to the wells in a 96 well V-bottom plate. Optimized concentration of in-house Syk enzyme (d...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Two μL of 10% DMSO in blank, substrate control and positive control wells and 2 μL of test compound in test wells was added. Thirteen μ...More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:2.5 μL of 10% DMSO or compound in 10% DMSO was added to the wells in a 96 well V-bottom plate. Optimized concentration of in-house Syk enzyme (d...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Two μL of 10% DMSO in blank, substrate control and positive control wells and 2 μL of test compound in test wells was added. Thirteen μ...More data for this Ligand-Target Pair