BDBM322740 2-(azepan-1-yl)-4-((4-(((2S,5S)-5- (hydroxymethyl)-1,4-dioxan-2-yl) methoxy)phenyl)amino)pyrimido[4,5- d]pyridazin-5(6H)-one::US10183944, Example 110::US10647720, Ex. # 110
SMILES OC[C@H]1CO[C@H](COc2ccc(Nc3nc(nc4cn[nH]c(=O)c34)N3CCCCCC3)cc2)CO1
InChI Key InChIKey=ZTOSNNCAKKWDQE-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 322740
Affinity DataIC50: 10nMAssay Description:2.5 μL of 10% DMSO or compound in 10% DMSO was added to the wells in a 96 well V-bottom plate. Optimized concentration of in-house Syk enzyme (d...More data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Two μL of 10% DMSO in blank, substrate control and positive control wells and 2 μL of test compound in test wells was added. Thirteen μ...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:2.5 μL of 10% DMSO or compound in 10% DMSO was added to the wells in a 96 well V-bottom plate. Optimized concentration of in-house Syk enzyme (d...More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Two μL of 10% DMSO in blank, substrate control and positive control wells and 2 μL of test compound in test wells was added. Thirteen μ...More data for this Ligand-Target Pair