BDBM322642 2-(4-(4-(5-oxo-2-phenyl-5,6- dihydropyrimido[4,5-d]pyridazin-4- ylamino)phenyl)piperazin-1-yl) acetic acid::US10183944, Example 12::US10647720, Ex. # 12
SMILES OC(=O)CN1CCN(CC1)c1ccc(Nc2nc(nc3cn[nH]c(=O)c23)-c2ccccc2)cc1
InChI Key InChIKey=FLLSFRYKFVEGIQ-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 322642
Affinity DataIC50: 50nMAssay Description:2.5 μL of 10% DMSO or compound in 10% DMSO was added to the wells in a 96 well V-bottom plate. Optimized concentration of in-house Syk enzyme (d...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Two μL of 10% DMSO in blank, substrate control and positive control wells and 2 μL of test compound in test wells was added. Thirteen μ...More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:2.5 μL of 10% DMSO or compound in 10% DMSO was added to the wells in a 96 well V-bottom plate. Optimized concentration of in-house Syk enzyme (d...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Two μL of 10% DMSO in blank, substrate control and positive control wells and 2 μL of test compound in test wells was added. Thirteen μ...More data for this Ligand-Target Pair