BDBM322399 (R)-7-chloro-6-fluoro-N-(1'-azaspiro[cyclopropane-1,2'-bicyclo[2.2.2]octan]-3'-yl)benzo[b]thiophene-2-carboxamide::US10183938, Compound (R)-158

SMILES Fc1ccc2cc(sc2c1Cl)C(=O)N[C@@H]1C2CCN(CC2)C11CC1

InChI Key InChIKey=RKFZJZNWZIIGFB-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 322399   

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Axovant Sciences

US Patent
LigandPNGBDBM322399(US10183938, Compound (R)-158 | (R)-7-chloro-6-fluo...)
Affinity DataKi:  200nMAssay Description:The ability of compounds to displace binding of radioactive ligands from human α7 nAChR was determined, as a measure of the affinity of the comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
Go to US Patent

Target5-hydroxytryptamine receptor 3A(Human)
Axovant Sciences

US Patent
LigandPNGBDBM322399(US10183938, Compound (R)-158 | (R)-7-chloro-6-fluo...)
Affinity DataKi:  370nMAssay Description:[3H]BRL 43694 competition binding assay was performed under contract by Cerep Poitiers, France following the methods described in Hope, A. G et al., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
Go to US Patent