BDBM322282 6-fluoro-N-(1'-azaspiro[cyclopropane-1,2'-bicyclo[2.2.2]octan]-3'-yl)benzo[b]thiophene-2-carboxamide::US10183938, Compound 61a

SMILES Fc1ccc2cc(sc2c1)C(=O)NC1C2CCN(CC2)C11CC1

InChI Key InChIKey=RKLAVCVKEGHMQO-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 322282   

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Axovant Sciences

US Patent
LigandPNGBDBM322282(US10183938, Compound 61a | 6-fluoro-N-(1'-azaspiro...)
Affinity DataKi:  220nMAssay Description:The ability of compounds to displace binding of radioactive ligands from human α7 nAChR was determined, as a measure of the affinity of the comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
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Target5-hydroxytryptamine receptor 3A(Human)
Axovant Sciences

US Patent
LigandPNGBDBM322282(US10183938, Compound 61a | 6-fluoro-N-(1'-azaspiro...)
Affinity DataKi:  1.50E+3nMAssay Description:[3H]BRL 43694 competition binding assay was performed under contract by Cerep Poitiers, France following the methods described in Hope, A. G et al., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
Go to US Patent