BDBM322193 (R)-7-chloro-N-(2,2-dimethylquinuclidin-3-yl)benzo[b]thiophene-2-carboxamide::US10183938, Compound (R)-3

SMILES CC1(C)[C@H](NC(=O)c2cc3cccc(Cl)c3s2)C2CCN1CC2

InChI Key InChIKey=HRWKDXOKUOFVIB-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 322193   

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Axovant Sciences

US Patent
LigandPNGBDBM322193(US10183938, Compound (R)-3 | (R)-7-chloro-N-(2,2-d...)
Affinity DataKi:  110nMAssay Description:The ability of compounds to displace binding of radioactive ligands from human α7 nAChR was determined, as a measure of the affinity of the comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
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Target5-hydroxytryptamine receptor 3A(Human)
Axovant Sciences

US Patent
LigandPNGBDBM322193(US10183938, Compound (R)-3 | (R)-7-chloro-N-(2,2-d...)
Affinity DataKi:  270nMAssay Description:[3H]BRL 43694 competition binding assay was performed under contract by Cerep Poitiers, France following the methods described in Hope, A. G et al., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
Go to US Patent