BDBM322041 (S,E)-3-(2-((5-Methyl-2H-tetrazol-2-yl)methyl)-4-(trifluoromethyl)phenyl)-1-(2-(trifluoromethyl)pyrrolidin-1-yl)prop-2-en-1-one::US10183025, Example 137::US9763957, Example 137

SMILES Cc1nnn(Cc2cc(ccc2\C=C\C(=O)N2CCC[C@H]2C(F)(F)F)C(F)(F)F)n1

InChI Key InChIKey=MVJMXJBYQSCYCR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 322041   

TargetAutotaxin(Human)
Novartis

US Patent
LigandPNGBDBM322041(US10183025, Example 137 | (S,E)-3-(2-((5-Methyl-2H...)
Affinity DataIC50: 7.5nMAssay Description:Reagents LPC (oleoyl (18:1)) was purchased from Avanti Polar Lipids (Alabaster, Ala.) and solubilized in methanol to 20 mM. Amplex Red was obtained f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
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TargetAutotaxin(Human)
Novartis

US Patent
LigandPNGBDBM322041(US10183025, Example 137 | (S,E)-3-(2-((5-Methyl-2H...)
Affinity DataIC50: 7.5nMAssay Description:Method All experimental measurements were performed in black 384 well polystyrene (low volume, round bottom, Corning (3676)) plates. PerkinElmer EnVi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2019
Entry Details
Go to US Patent