BDBM32201 8-[5-(propan-2-ylamino)pentan-2-ylamino]-6-quinolinol::8-[5-(propan-2-ylamino)pentan-2-ylamino]quinolin-6-ol::8-[[4-(isopropylamino)-1-methyl-butyl]amino]quinolin-6-ol::cid_245089

SMILES CC(C)NCCCC(C)Nc1cc(O)cc2cccnc12

InChI Key InChIKey=BQXVFZVEBYAYEJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 32201   

TargetHeat shock protein HSP 90-alpha(Human)
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM32201(cid_245089 | 8-[5-(propan-2-ylamino)pentan-2-ylami...)
Affinity DataIC50: 1.56E+3nMpH: 7.4 T: 2°CAssay Description:A fluorescence polarization based HTS assay has been developed and optimized for the identification of Hsp90 inhibitors by using tumor cell lysate Hs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2009
Entry Details
PCBioAssay
TargetHeat shock protein HSP 90-alpha(Human)
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM32201(cid_245089 | 8-[5-(propan-2-ylamino)pentan-2-ylami...)
Affinity DataIC50: 1.00E+4nMAssay Description:Emory Chemistry-Biology Discovery Center Assay Overview: MLSCN Grant: 1 X01MH78953-01 Hsp90 is a chaperon with important roles in maintaining transfo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2011
Entry Details
PCBioAssay
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM32201(cid_245089 | 8-[5-(propan-2-ylamino)pentan-2-ylami...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of Hsp90 in human MCF7 cell lysates assessed as interaction with Cy3b-conjugated geldanamycin by FP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed