BDBM32200 8-[5-(diethylamino)pentylamino]-6-quinolinol::8-[5-(diethylamino)pentylamino]quinolin-6-ol::cid_245086

SMILES CCN(CC)CCCCCNc1cc(O)cc2cccnc12

InChI Key InChIKey=QCFWRPRHNQZRFT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 32200   

TargetHeat shock protein HSP 90-alpha(Human)
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM32200(cid_245086 | 8-[5-(diethylamino)pentylamino]-6-qui...)
Affinity DataIC50: 6.25E+3nMpH: 7.4 T: 2°CAssay Description:A fluorescence polarization based HTS assay has been developed and optimized for the identification of Hsp90 inhibitors by using tumor cell lysate Hs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2009
Entry Details
PCBioAssay
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM32200(cid_245086 | 8-[5-(diethylamino)pentylamino]-6-qui...)
Affinity DataIC50: 730nMAssay Description:Inhibition of Hsp90 in human MCF7 cell lysates assessed as interaction with Cy3b-conjugated geldanamycin by FP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM32200(cid_245086 | 8-[5-(diethylamino)pentylamino]-6-qui...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Hsp90 in human MCF7 cells assessed as Her2 level after 24 hrs by Western blotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed