BDBM321927 (E)-ethyl 1-(3-(4-Chloro-2-((5-methyl-2H-tetrazol-2-yl)methyl)phenyl)acryloyl)piperidine-4-carboxylate::US10183025, Example 49.9::US9763957, Example 49.9

SMILES CCOC(=O)C1CCN(CC1)C(=O)\C=C\c1ccc(Cl)cc1Cn1nnc(C)n1

InChI Key InChIKey=XETNSXPMANGIML-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 321927   

TargetAutotaxin(Human)
Novartis

US Patent
LigandPNGBDBM321927((E)-ethyl 1-(3-(4-Chloro-2-((5-methyl-2H-tetrazol-...)
Affinity DataIC50: 5.90nMAssay Description:Reagents LPC (oleoyl (18:1)) was purchased from Avanti Polar Lipids (Alabaster, Ala.) and solubilized in methanol to 20 mM. Amplex Red was obtained f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
Go to US Patent

TargetAutotaxin(Human)
Novartis

US Patent
LigandPNGBDBM321927((E)-ethyl 1-(3-(4-Chloro-2-((5-methyl-2H-tetrazol-...)
Affinity DataIC50: 5.90nMAssay Description:Method All experimental measurements were performed in black 384 well polystyrene (low volume, round bottom, Corning (3676)) plates. PerkinElmer EnVi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2019
Entry Details
Go to US Patent