BDBM321893 (E)-3-(4-Chloro-2-((5-methyl-2H-tetrazol-2-yl)methyl)phenyl)-1-(4-(4-methyl-1H-pyrazol-1-yl)piperidin-1-yl)prop-2-en-1-one::US10183025, Example 28::US9763957, Example 28

SMILES Cc1cnn(c1)C1CCN(CC1)C(=O)\C=C\c1ccc(Cl)cc1Cn1nnc(C)n1

InChI Key InChIKey=SNDDWGCYNZLXPZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 321893   

TargetAutotaxin(Human)
Novartis

US Patent
LigandPNGBDBM321893((E)-3-(4-Chloro-2-((5-methyl-2H-tetrazol-2-yl)meth...)
Affinity DataIC50: 6.30nMAssay Description:Reagents LPC (oleoyl (18:1)) was purchased from Avanti Polar Lipids (Alabaster, Ala.) and solubilized in methanol to 20 mM. Amplex Red was obtained f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
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TargetAutotaxin(Human)
Novartis

US Patent
LigandPNGBDBM321893((E)-3-(4-Chloro-2-((5-methyl-2H-tetrazol-2-yl)meth...)
Affinity DataIC50: 6.30nMAssay Description:Method All experimental measurements were performed in black 384 well polystyrene (low volume, round bottom, Corning (3676)) plates. PerkinElmer EnVi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2019
Entry Details
Go to US Patent