BDBM321868 US10183025, Example 5a::US9763957, Example 5b

SMILES Cc1noc(n1)[C@@H]1CCCCN1C(=O)\C=C\c1ccc(cc1Cn1nnc(C)n1)C(F)(F)F

InChI Key InChIKey=FSEITZAJBZOSAZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 321868   

TargetAutotaxin(Human)
Novartis

US Patent
LigandPNGBDBM321868(US10183025, Example 5a | US9763957, Example 5b)
Affinity DataIC50: 3.5nMAssay Description:Reagents LPC (oleoyl (18:1)) was purchased from Avanti Polar Lipids (Alabaster, Ala.) and solubilized in methanol to 20 mM. Amplex Red was obtained f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
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TargetAutotaxin(Human)
Novartis

US Patent
LigandPNGBDBM321868(US10183025, Example 5a | US9763957, Example 5b)
Affinity DataIC50: 120nMAssay Description:Method All experimental measurements were performed in black 384 well polystyrene (low volume, round bottom, Corning (3676)) plates. PerkinElmer EnVi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2019
Entry Details
Go to US Patent