BDBM321864 (S,E)-1-(2-(5-Methyl-1,3,4-oxadiazol-2-yl)piperidin-1-yl)-3-(2-((5-methyl-2H-tetrazol-2-yl)methyl)-4-(trifluoromethyl)phenyl)prop-2-en-1-one::US10183025, Example 1::US9763957, Example 1

SMILES CCOC(=O)c1c(C)ccnc1O[C@@H]1CC[C@@H](C)N(C1)C(=O)c1ccccc1-n1nccn1

InChI Key InChIKey=DSWPTVKCBCROGK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 321864   

TargetAutotaxin(Human)
Novartis

US Patent
LigandPNGBDBM321864((S,E)-1-(2-(5-Methyl-1,3,4-oxadiazol-2-yl)piperidi...)
Affinity DataIC50: 8.80nMAssay Description:Reagents LPC (oleoyl (18:1)) was purchased from Avanti Polar Lipids (Alabaster, Ala.) and solubilized in methanol to 20 mM. Amplex Red was obtained f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
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TargetAutotaxin(Human)
Novartis

US Patent
LigandPNGBDBM321864((S,E)-1-(2-(5-Methyl-1,3,4-oxadiazol-2-yl)piperidi...)
Affinity DataIC50: 8.80nMAssay Description:Method All experimental measurements were performed in black 384 well polystyrene (low volume, round bottom, Corning (3676)) plates. PerkinElmer EnVi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2019
Entry Details
Go to US Patent