BDBM32185 6-[5-(3-methoxy-4-oxidanyl-phenyl)pyrazolidin-3-ylidene]cyclohexa-2,4-dien-1-one::6-[5-(4-hydroxy-3-methoxy-phenyl)pyrazolidin-3-ylidene]cyclohexa-2,4-dien-1-one::6-[5-(4-hydroxy-3-methoxyphenyl)-3-pyrazolidinylidene]-1-cyclohexa-2,4-dienone::6-[5-(4-hydroxy-3-methoxyphenyl)pyrazolidin-3-ylidene]cyclohexa-2,4-dien-1-one::CHEMBL210638::TG2-101-2::cid_6790395

SMILES COc1cc(ccc1O)C1CC(N=N1)c1ccccc1O

InChI Key InChIKey=KHERWPKMPPANRP-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 32185   

TargetHeat shock protein HSP 90-alpha(Human)
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM32185(6-[5-(4-hydroxy-3-methoxyphenyl)-3-pyrazolidinylid...)
Affinity DataIC50: 5.00E+4nMpH: 7.4 T: 2°CAssay Description:A fluorescence polarization based HTS assay has been developed and optimized for the identification of Hsp90 inhibitors by using tumor cell lysate Hs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2009
Entry Details
PCBioAssay
TargetHeat shock protein HSP 90-alpha(Human)
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM32185(6-[5-(4-hydroxy-3-methoxyphenyl)-3-pyrazolidinylid...)
Affinity DataIC50: 5.10E+4nMAssay Description:Emory Chemistry-Biology Discovery Center Assay Overview: MLSCN Grant: 1 X01MH78953-01 Hsp90 is a chaperon with important roles in maintaining transfo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2011
Entry Details
PCBioAssay
TargetReceptor tyrosine-protein kinase erbB-2(Human)
The University of Kansas

Curated by ChEMBL
LigandPNGBDBM32185(6-[5-(4-hydroxy-3-methoxyphenyl)-3-pyrazolidinylid...)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of Her2 in SKBr3 cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
The University of Kansas

Curated by ChEMBL
LigandPNGBDBM32185(6-[5-(4-hydroxy-3-methoxyphenyl)-3-pyrazolidinylid...)
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of Hsp90 by recombinant ATPase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed