BDBM32184 CHEMBL209511::N-(4-chloranyl-2-oxidanyl-phenyl)benzenesulfonamide::N-(4-chloro-2-hydroxy-phenyl)benzenesulfonamide::N-(4-chloro-2-hydroxyphenyl)benzenesulfonamide::TG2-101-1::cid_800888

SMILES Oc1cc(Cl)ccc1NS(=O)(=O)c1ccccc1

InChI Key InChIKey=RONKFMHPAFRXHH-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 32184   

TargetHeat shock protein HSP 90-alpha(Human)
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM32184(CHEMBL209511 | N-(4-chloro-2-hydroxyphenyl)benzene...)
Affinity DataIC50: 5.00E+4nMpH: 7.4 T: 2°CAssay Description:A fluorescence polarization based HTS assay has been developed and optimized for the identification of Hsp90 inhibitors by using tumor cell lysate Hs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2009
Entry Details
PCBioAssay
TargetHeat shock protein HSP 90-alpha(Human)
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM32184(CHEMBL209511 | N-(4-chloro-2-hydroxyphenyl)benzene...)
Affinity DataIC50: 6.00E+4nMAssay Description:Emory Chemistry-Biology Discovery Center Assay Overview: MLSCN Grant: 1 X01MH78953-01 Hsp90 is a chaperon with important roles in maintaining transfo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2011
Entry Details
PCBioAssay
TargetReceptor tyrosine-protein kinase erbB-2(Human)
The University of Kansas

Curated by ChEMBL
LigandPNGBDBM32184(CHEMBL209511 | N-(4-chloro-2-hydroxyphenyl)benzene...)
Affinity DataIC50: 3.10E+4nMAssay Description:Inhibition of Her2 in SKBr3 cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
The University of Kansas

Curated by ChEMBL
LigandPNGBDBM32184(CHEMBL209511 | N-(4-chloro-2-hydroxyphenyl)benzene...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of Hsp90 by recombinant ATPase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed