BDBM321439 6-butyl-4-[2,5-dimethoxy-4-(morpholine-4-carbonyl)phenyl]-2-methyl-1H-pyrrolo[2,3-c]pyridin-7-one::US10183009, Example 121

SMILES CCCCn1cc(-c2cc(OC)c(cc2OC)C(=O)N2CCOCC2)c2cc(C)[nH]c2c1=O

InChI Key InChIKey=MITBTHHFLRBDQI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 321439   

TargetBromodomain-containing protein 9 [134-239](Human)
Genentech

US Patent
LigandPNGBDBM321439(6-butyl-4-[2,5-dimethoxy-4-(morpholine-4-carbonyl)...)
Affinity DataIC50: 17nMAssay Description:His/Flag epitope tagged BRD9134-239 was cloned, expressed, and purified to homogeneity. BRD9 binding and inhibition was assessed by monitoring the en...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
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