BDBM321388 3-(6-butyl-7-oxo-1H-pyrrolo[2,3-c]pyridin-4-yl)-4-methoxy-benzonitrile::US10183009, Example 46

SMILES CCCCn1cc(-c2cc(ccc2OC)C#N)c2cc[nH]c2c1=O

InChI Key InChIKey=KMCTTWIADWEWSX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 321388   

TargetBromodomain-containing protein 9 [134-239](Human)
Genentech

US Patent
LigandPNGBDBM321388(3-(6-butyl-7-oxo-1H-pyrrolo[2,3-c]pyridin-4-yl)-4-...)
Affinity DataIC50: 46nMAssay Description:His/Flag epitope tagged BRD9134-239 was cloned, expressed, and purified to homogeneity. BRD9 binding and inhibition was assessed by monitoring the en...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent