BDBM32108 6-keto-7,8,9,10-tetrahydrophenothiazine-3-carboxylic acid methyl ester::6-oxo-7,8,9,10-tetrahydrophenothiazine-3-carboxylic acid methyl ester::MLS000100349::SMR000082651::cid_1258835::methyl 4-oxo-2,3,4,10-tetrahydro-1H-phenothiazine-7-carboxylate::methyl 6-oxidanylidene-7,8,9,10-tetrahydrophenothiazine-3-carboxylate::methyl 6-oxo-7,8,9,10-tetrahydrophenothiazine-3-carboxylate

SMILES COC(=O)c1ccc2N=C3CCCC(=O)C3Sc2c1

InChI Key InChIKey=YDPBCQQIPGCGPO-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 32108   

TargetHeat shock protein HSP 90-alpha(Human)
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM32108(6-oxo-7,8,9,10-tetrahydrophenothiazine-3-carboxyli...)
Affinity DataIC50: 1.09E+4nMpH: 7.4 T: 2°CAssay Description:A fluorescence polarization based HTS assay has been developed and optimized for the identification of Hsp90 inhibitors by using tumor cell lysate Hs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2009
Entry Details
PCBioAssay
TargetGlycoprotein 42(HHV-4)
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM32108(6-oxo-7,8,9,10-tetrahydrophenothiazine-3-carboxyli...)
Affinity DataIC50: 2.22E+3nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Theodore Jardetzky; Northw...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2011
Entry Details
PCBioAssay
TargetProtein Rev(Human immunodeficiency virus type 1)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM32108(6-oxo-7,8,9,10-tetrahydrophenothiazine-3-carboxyli...)
Affinity DataIC50: 7.54E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2011
Entry Details
PCBioAssay
TargetFemale germline-specific tumor suppressor gld-1(Caenorhabditis elegans)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM32108(6-oxo-7,8,9,10-tetrahydrophenothiazine-3-carboxyli...)
Affinity DataIC50: 6.12E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2011
Entry Details
PCBioAssay
TargetFibrinogen beta chain [164-491](Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM32108(6-oxo-7,8,9,10-tetrahydrophenothiazine-3-carboxyli...)
Affinity DataIC50: 1.79E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: Harvard Medical School/Massachuset...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2014
Entry Details
PCBioAssay
TargetFibrinogen beta chain [164-491](Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM32108(6-oxo-7,8,9,10-tetrahydrophenothiazine-3-carboxyli...)
Affinity DataIC50: 8.33E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: Harvard Medical School/Massachuset...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2014
Entry Details
PCBioAssay