BDBM321049 US10174040, Example 132::[(2R,3S,4R,5R)-5-[4-Amino-5-[2-(2,6-difluorophenyl)ethynyl]pyrrolo[2,3-d]pyrimidin-7-yl]-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl sulfamate

SMILES Nc1ncnc2n(cc(C#Cc3c(F)cccc3F)c12)[C@@H]1O[C@H](COS(N)(=O)=O)[C@@H](O)[C@H]1O

InChI Key InChIKey=OLUCSJAMKYLUQU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 321049   

TargetNEDD8-conjugating enzyme UBE2F(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM321049(US10174040, Example 132 | [(2R,3S,4R,5R)-5-[4-Amin...)
Affinity DataIC50: 3nMAssay Description:A purified NAE (heterodimer of APPBP1 and UBA3) solution was prepared in the following manner. The human APPBP1 gene (NCBI Reference Sequence number:...More data for this Ligand-Target Pair
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Date in BDB:
5/16/2019
Entry Details
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