BDBM320529 4-(1-{[6-(Morpholin-4-yl)-2-(1H-pyrazol-4-yl)-9H-purin-8-yl]carbonyl}piperidin-4-yl)morpholin-3-one::US10174035, Compound 74

SMILES O=C(N1CCC(CC1)N1CCOCC1=O)c1nc2c(nc(nc2[nH]1)-c1cn[nH]c1)N1CCOCC1

InChI Key InChIKey=IGHJVHGVQYWCHU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 320529   

LigandPNGBDBM320529(US10174035, Compound 74 | 4-(1-{[6-(Morpholin-4-yl...)
Affinity DataIC50: 8nMAssay Description:The Kinase-Glo luminescent kinase assay kit (from Promega) was used to measure kinase activity. In this assay, amount of ATP remaining in solution fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent