BDBM320468 US10174035, Compound 14::[4-(2-Hydroxypropan-2-yl)piperidin-1-yl][2-(1-methyl-1H-pyrazol-4-yl)-6-(morpholin-4-yl)-9H-purin-8-yl]methanone

SMILES Cn1cc(cn1)-c1nc(N2CCOCC2)c2nc([nH]c2n1)C(=O)N1CCC(CC1)C(C)(C)O

InChI Key InChIKey=IPVDCPNVPWZJFU-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 320468   

LigandPNGBDBM320468(US10174035, Compound 14 | [4-(2-Hydroxypropan-2-yl...)
Affinity DataIC50: 16nMAssay Description:The Kinase-Glo luminescent kinase assay kit (from Promega) was used to measure kinase activity. In this assay, amount of ATP remaining in solution fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

LigandPNGBDBM320468(US10174035, Compound 14 | [4-(2-Hydroxypropan-2-yl...)
Affinity DataIC50: 16nMAssay Description:The Kinase-Glo luminescent kinase assay kit (from Promega) was used to measure kinase activity. In this assay, amount of ATP remaining in solution fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

LigandPNGBDBM320468(US10174035, Compound 14 | [4-(2-Hydroxypropan-2-yl...)
Affinity DataIC50: 584nMAssay Description:The Kinase-Glo luminescent kinase assay kit (from Promega) was used to measure kinase activity. In this assay, amount of ATP remaining in solution fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

TargetPhosphatidylinositol 3-kinase regulatory subunit alpha(Human)
Daiichi Sankyo

US Patent
LigandPNGBDBM320468(US10174035, Compound 14 | [4-(2-Hydroxypropan-2-yl...)
Affinity DataIC50: 1.00E+3nMAssay Description:The Kinase-Glo luminescent kinase assay kit (from Promega) was used to measure kinase activity. In this assay, amount of ATP remaining in solution fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

TargetPhosphatidylinositol 3-kinase regulatory subunit beta(Human)
Daiichi Sankyo

US Patent
LigandPNGBDBM320468(US10174035, Compound 14 | [4-(2-Hydroxypropan-2-yl...)
Affinity DataIC50: 1.00E+4nMAssay Description:The Kinase-Glo luminescent kinase assay kit (from Promega) was used to measure kinase activity. In this assay, amount of ATP remaining in solution fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent