BDBM320385 2-cyclopentyl-1H-pyrrolo[3,2- b]pyridine-7-carboxylic acid::US10174026, Example 29::US9738637, Example 29

SMILES OC(=O)c1ccnc2cc([nH]c12)C1CCCC1

InChI Key InChIKey=MJGNHAKBDPMKTA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 320385   

TargetLysine-specific demethylase 5A(Human)
Celgene Quantical Research

US Patent
LigandPNGBDBM320385(US10174026, Example 29 | 2-cyclopentyl-1H-pyrrolo[...)
Affinity DataIC50: 550nMAssay Description:The enzymatic assay of Jarid1A activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of test c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2019
Entry Details
Go to US Patent

TargetLysine-specific demethylase 5B(Human)
Celgene Quantical Research

US Patent
LigandPNGBDBM320385(US10174026, Example 29 | 2-cyclopentyl-1H-pyrrolo[...)
Affinity DataIC50: 550nMAssay Description:The ability of test compounds to inhibit the activity of Jarid1B was determined in 384-well plate format under the following reaction conditions: 0.8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2019
Entry Details
Go to US Patent

TargetLysine-specific demethylase 4C(Human)
Celgene Quantical Research

US Patent
LigandPNGBDBM320385(US10174026, Example 29 | 2-cyclopentyl-1H-pyrrolo[...)
Affinity DataIC50: 100nMAssay Description:The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2019
Entry Details
Go to US Patent